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Dideoxyinosine (didanosine) Powder Raw APIS Antiretroviral Drug

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  • Specifications

BuyDideoxyinosine (didanosine) Powder Raw APIS Antiretroviral Drug For Human Immunodeficiency Virus Infections Online CAS 890-38-0

 

Dideoxyinosine Specification

Item Specifications
Identincation A: IR comparison didanosine CRS
B:HPLC

Should meet the requirement

Water(K.F) ≤2.0%
Residue on ignition ≤0.2%
Heavy Metals ≤20ppm
Specific Optical rotation -24.0°~-28.0°(anhydrous)
Related substances Hypoxanthine≤0.5%
Inosine≤0.2%
2’-Deoxyinosine≤0.3%
3’-Deoxyinosine≤0.2%
2’,3’-anhydroinosine≤0.2%
Dideoxydidehydroinosine≤0.2%
2’,3’-dideoxyadenosine≤0.2%
5’-Deoxydideoxyadenosine≤0.2%
Any other impurity ≤0.1%
total≤1.0%
Assay (on the anhydrous basis) 98.0%~102.0%

 

What is Dideoxyinosine?

Dideoxyinosine is an antiretroviral drug used in the treatment of human immunodeficiency virus infections. ddI inhibits the enzyme reverse transcriptase, thereby restricting viral replication activity. Inside the body, ddI is converted to dideoxyadenosine, which becomes incorporated into the deoxyribonucleic acid chain, interrupting its normal sequence and making viral replication impossible. Also called didanosine.

 

Dideoxyinosine Application

Didanosine is used to treat HIV and AIDS. The medication has been approved for use in treating adults and children as young as two weeks old. Didanosine is not a cure for HIV or AIDS, but it can stop the HIV virus from multiplying and destroying healthy cells. Off-label didanosine uses include preventing HIV infection in people who have been exposed to the HIV viru

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