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Carbetapentane Citrate Powder Raw Antitussive (cough suppressant) Drug

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  • Specifications

Buy Carbetapentane Citrate Powder Raw Antitussive (cough suppressant) Drug Online CAS 23142-01-0

 

Carbetapentane Citrate Specification

Product Name: Carbetapentane Citrate
CAS: 23142-01-0
Standard: Enterprise Standard
Level: Medical grade
Content: 98%
Appearance: white powder
Packing: 25KG/ cardboard drum detachable
Category: Pharmaceutical raw materials
Area: Antitussives
Deferred products: (1) citric acid spray vetolide tablets (2) citric acid spray voramine drop pills
Use: Mainly used for dry cough and whooping cough caused by upper respiratory tract infection
Dosage: Oral: 25mg for adults, 3 to 4 times a day; children over 5 years old orally 6.25 ~ 12.5mg, 2 times or 3 times a day. 1. Occasionally mild dizziness, dry mouth, nausea, bloating, constipation and other adverse reactions, this is due to its atropine-like effect. 2. Glaucoma and heart failure patients with pulmonary blood stasis are hanged. 3. Many people should be combined with expectorants.

 

What is  carbetapentane?

Pentoxyverine (rINN) or carbetapentane is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold. It is sold over-the-counter in the United States as Solotuss, or in combination with other medications, especially decongestants. One such product is Certuss, a combination of guaifenesin and pentoxyverine.

 

Carbetapentane Citrate Certificate of Analysis

Product name Carbetapentane citrate
CAS No. 23142-01-0 Outer Packing 25kg/drum
Production date 2017.12.25 Shelf life 2020.12.24
Standard adopted CP2015
Items of analysis Specification Results
Appearance White or off-white crystalline or granular powder White granular powder
Solubility Soluble in water, soluble in ethanol; slightly soluble in chloroform; almost insoluble in ether Conforms
Melting point 88~93℃ 90.0~92℃
Identification 1 Take about 20mg of this product, add 2ml of water to dissolve, add 4 drops of dilute hydrochloric acid and a few drops of potassium ferrocyanide test solution, which will form a yellow-white crystal precipitate. Conforms
Identification 2 Take about 20mg of this product, add 10ml of water to dissolve, add 2 drops of dilute hydrochloric acid and a few drops of potassium dichromate test solution, which will produce a yellow precipitate. Conforms
Identification 3 The infrared absorption spectrum should be consistent with the control spectrum Conforms
Identification 4 This product showed the differentiation reaction of citrate Conforms
Clarity ≤3#(0.5g-5ml water) Conforms
relative substance Single impurity ≤ 0.2%; total impurities ≤ 1.0% Single impurity0.045%, total impurities 0.16%
Remaining solvent Ethanol ≤0.5%; tetrahydrofuran ≤0.072%; toluene ≤0.089% Ethanol 0.023%; tetrahydrofuran was not detected; toluene was not detected
Loss on drying ≤1.0% 0.06%
Residue on ignition ≤0.1% 0.08%
Heavy metal ≤0.0015% Conforms
Assay ≥98.5% 98.9%
Conclusion Qualified

 

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