Buy Raw Anticholinergic Bronchodilator APIs Tiotropium bromide (Spiriva) Powder Online
What is Tiotropium bromide?
Tiotropium bromide, originally marketed as Spiriva,[1] is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD)
Tiotropium bromide Basic Information
| Product Name |
Tiotropium bromide |
| CAS |
136310-93-5 |
| MF |
C19H22BrNO4S2 |
| MW |
472.42 |
| Apperance |
White Solid |
| Usage |
Muscarinic receptor antagonist. Bronchodilator |
Tiotropium bromide certifIcate Of Analysis
| Product name |
Tiotropium bromide |
| CAS No. |
136310-93-5 |
Outer Packing |
1kg/bag |
| Production date |
13th Jan 2018 |
Shelf life |
12th Jan 2020 |
| Standard adopted |
Enterprise Standard |
| Items of analysis |
Specification |
Results |
| Appearance |
White or yellowish white powder or crystal |
Conforms |
| Solubility |
Slightly soluble in water, soluble in methanol, insoluble in dichloromethane |
Conforms |
| Identification |
(1) IR infrared spectrum; (2) Typical reaction of bromide |
Conforms |
| Residue on ignition |
≤0.1% |
0.06% |
| Water |
≤0.5% |
0.36% |
| Impurity C |
≤0.3% |
Conforms |
| Impurity F |
≤0.15% |
Conforms |
| Impurities A,E |
≤0.15% |
Conforms |
| Impurities G,H |
≤0.1% |
Conforms |
| Unknown Impurities |
≤0.1% |
Conforms |
| Total Impurities |
≤0.3% |
0.29% |
| Isomer |
≤0.1% |
0.09% |
| Assay |
≥99.0% |
99.71% |
| Graininess |
D100：≤20 µm |
Conforms |
| Conclusion |
Qualified |
Tiotropium bromide Medical Uses
Tiotropium is used for maintenance treatment of chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema.[3] It is not however used for acute exacerbations
Tiotropium bromide side effects
dry mouth and/or throat irritation. Rarely (<0.1% of patients) treatment is associated with:urinary retention, constipation, acute angle closure glaucoma, palpitations (notably supraventricular tachycardia and atrial fibrillation) and/or allergy (rash, angioedema, anaphylaxis).
